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HEAD TO HEAD
Dimitris Papadopoulos: biodecision and Convai Innovations: laya, compared on what they decide, where they run, what they cost and what their publishers report.
| Property | lighteternal/biodecision | convai-innovations/laya |
|---|---|---|
| Summary | A 4B biomedical decision model by Dimitris Papadopoulos: Qwen3.5-4B tuned with Together AI's Tev1 recipe on 1.75M pharma, clinical-trial and literature decisions. One forward pass gives a temperature-scaled probability per option. Research use only. | An open-weights System One model from Convai Innovations. A fully fine-tuned ModernBERT-large encoder with a from-scratch decision head that scores one marker per option and answers every question in a single 33–39 ms pass. Runs on your own CPU or GPU. |
| Decides | choice, score, noul, classify | choice, score, noul, classify, route |
| Architecture | biodecision | laya |
| Fine-tuned from | qwen/qwen3.5-4b | answerdotai/modernbert-large |
| License | Research use only (several training sources are non-commercial); not validated for patient care | apache-2.0 |
| Availability | Open weights | Open weights |
| Hosted by | — | — |
| Input price | — | — |
| Decision accuracy | 75.3% | — |
| Calibration error | — | — |
| Valid action rate | — | — |
| Median latency | 39 ms | 39.5 ms |
| p95 latency | — | — |
| Evaluation suite | BioDecision v2 held-out test set (63,432 overlap-screened decisions from public biomedical benchmarks; the maker's own split) | — |
| Latest version | 2.0.0 | 2026.09.25 |
| Variants | LICENSE | multilingual, tokenizer, typed-decisions, eval, encoder |
| Size of latest version | 8.7 GB | 2.2 GB |
| Files | 15 | 19 |
| Downloads | 0 | 139 |
| Stars | 0 | 0 |
| Tags | system-one, qwen, biomedical, clinical-trials, jev-inspired, research-only, 4b | system-one, encoder, modernbert, rlcd, multilingual, 421m |
| Updated | Oct 7, 2026 | Oct 7, 2026 |
Figures are from each model’s manifest; accuracy and latency are what the publishers report, on their own suites and hardware. Add a third model.
biodecision is from Dimitris Papadopoulos and laya from Convai Innovations. Both have open weights you can download and run. Both answer choice, score, noul and classify questions. Only laya answers route. laya is the smaller model, at 421M parameters to 4.0B. biodecision is licensed other; laya, apache-2.0.
Only biodecision publishes an accuracy figure (75.3% on BioDecision v2 held-out test set (63,432 overlap-screened decisions from public biomedical benchmarks; the maker's own split)); laya does not, so there is no comparison to make without your own test.
biodecision: Free (open weights). laya: Free (open weights). Open weights cost nothing per call beyond your own hardware.
By their publishers’ figures, biodecision answers in about 39 ms at the median and laya in about 39.5 ms — measured on different hardware, so treat it as a rough guide.
Yes, both: systemone pull lighteternal/biodecision and systemone pull convai-innovations/laya download the weights.