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Dimitris Papadopoulos: biodecision and StartLux: startlux-decision, compared on what they decide, where they run, what they cost and what their publishers report.
| Property | lighteternal/biodecision | startlux/startlux-decision |
|---|---|---|
| Summary | A 4B biomedical decision model by Dimitris Papadopoulos: Qwen3.5-4B tuned with Together AI's Tev1 recipe on 1.75M pharma, clinical-trial and literature decisions. One forward pass gives a temperature-scaled probability per option. Research use only. | StartLux's decision family in six sizes, 0.8B to a 35B-A3B mixture of experts. All questions in a request are answered in one forward pass, with a probability for every option, through a TypeSafe /v1/systemone-compatible server. Text, JSON or images, up to 256K tokens. |
| Decides | choice, score, noul, classify | choice, score, noul |
| Architecture | biodecision | startlux-decision |
| Fine-tuned from | qwen/qwen3.5-4b | — |
| License | Research use only (several training sources are non-commercial); not validated for patient care | cc-by-nc-4.0 |
| Availability | Open weights | Open weights |
| Hosted by | — | — |
| Input price | — | — |
| Decision accuracy | 75.3% | 88.3% |
| Calibration error | — | — |
| Valid action rate | — | — |
| Median latency | 39 ms | 26 ms |
| p95 latency | — | — |
| Evaluation suite | BioDecision v2 held-out test set (63,432 overlap-screened decisions from public biomedical benchmarks; the maker's own split) | JevBench public set (231 items; 204 correct), maker's run |
| Latest version | 2.0.0 | 2026.10 |
| Variants | LICENSE | LICENSE, NOTICE, startlux_decision |
| Size of latest version | 8.7 GB | 8.7 GB |
| Files | 15 | 23 |
| Downloads | 0 | 3 |
| Stars | 0 | 0 |
| Tags | system-one, qwen, biomedical, clinical-trials, jev-inspired, research-only, 4b | system-one, qwen, non-commercial, gguf, cuda-graphs, vision, mlx, 4.7b |
| Updated | Oct 7, 2026 | Oct 7, 2026 |
Figures are from each model’s manifest; accuracy and latency are what the publishers report, on their own suites and hardware. Add a third model.
biodecision is from Dimitris Papadopoulos and startlux-decision from StartLux. Both have open weights you can download and run. Both answer choice, score and noul questions. Only biodecision answers classify. biodecision is the smaller model, at 4.0B parameters to 4.7B. biodecision is licensed other; startlux-decision, cc-by-nc-4.0.
They report on different suites — biodecision 75.3% on BioDecision v2 held-out test set (63,432 overlap-screened decisions from public biomedical benchmarks; the maker's own split), startlux-decision 88.3% on JevBench public set (231 items; 204 correct), maker's run — so the numbers do not rank them. Test both on your own labelled examples.
biodecision: Free (open weights). startlux-decision: Free (open weights). Open weights cost nothing per call beyond your own hardware.
By their publishers’ figures, startlux-decision answers in about 26 ms at the median and biodecision in about 39 ms — measured on different hardware, so treat it as a rough guide.
Yes, both: systemone pull lighteternal/biodecision and systemone pull startlux/startlux-decision download the weights.